Obesity Connected to a Brain Protein?
The study showed how a protein called SH2B1 can regulate body weight, the use of energy, or the action of leptin and insulin. It may also moderate the effect of a high-fat diet on weight balance.
An earlier study by the same team had showed that mice with a lack of SH2B1 become diabetic, obese, or even unable to stop eating because their brains lost the ability to sense signals from leptin and insulin that indicate when to stop the food intake. The experiments included different types of mice: some that were normal, some genetically altered so they have SH2B1 only in the brain, and mice that didn`t had the gene responsible for SH2B1.
The study showed that restoring the level of SH2B1 in the brain lead to a re-establishment of metabolic disorders in case of mice with a lack of SH2B1 and also improved the brain`s ability to respond to leptin signals. The mice that were modified so they could produce extra SH2B1 responded to leptin signals and didn`t become obese even if they were on a high-fat diet.
SH2B1 seems to have a regulatory role in the system that is processing leptin and insulin signals, according to researcher Liangyou Rui. The imbalance between energy intake and energy use leads to obesity, but it may be caused by alterations of leptin and insulin signals, says Rui.
Related Tags: weight loss, bmi calculator, calorie counter, calorie calculator, diet planner, menu planner, workout planner, weight loss tools, nutritional information
To read the rest of this article, go to www.projectweightloss.com , an online weight loss community featuring calorie counter, BMI calculator, diet planner, workout planner and other weight loss tools. Visit www.projectweightloss.com and start losing weight today!
Your Article Search Directory : Find in ArticlesRecent articles in this category:
- Dental Insurance For Individual Can Be Of Help At Time
Dental problem may cost one a lot of money and pain. But, practicing a reasonable care could decreas - Personal Trainer For Perfect Health
There is a general misconception that need for a fitness trainer comes for novice or from those who - Varicose Veins - Causes, Symptoms, Treatment
The majority of people after thirty notice the changes that appear with the maturing. In this case t - Scenar Therapy - Self-treatment Or Healing Partnership
Do you want to learn about a device which will help you to ease your pain? If you get this kind of a - Scenar - 5 "no, Nos" Of Scenar
Are you fed up with the pain in your body? Various parts of our body seem to ache due to different r - Scenar Device - 5 Tips On Travelling With Your Scenar (skenar) Device
You might be aware of scenar which has become quite popular these days. This is actually the acronym - Scenar Therapy - How To Treat Your Pet With Scenar
There are many alternative methods of treatment that are being invented these days. Lots of people a - Your Options For The Treatment For Appendicitis
Appendicitis is considered to be a surgical illness. Due to its severe character, the treatment for - How To Choose The Right Copd Medication
Chronic obstructive pulmonary disease or COPD does not have any cure. But with the help of medicines - Septic Arthritis: Infectious Agents Penetrate Joints' Spaces
Another major type of arthritis is septic arthritis, which is also known in various terms like: pyog
Most viewed articles in this category:
- Drugs - the Last Alternative for Adhd in Kids
Anyone over the age of thirty who has grown up with ADHD understands that there was not much help av - Foods To Eat To Gain Weight
Malnutrition has the same degree of problem as obesity. There are people who are too skinny, they fi - Understanding Postpartum Clothing
The same way most pregnant women dream of the day when they will begin showing for wearing maternity - Kegel Exercising for Bladder Control and Enhanced Sexual Pleasure
Kegel exercises strengthen the muscles of the pelvic floor, thereby improving the urethra and/or rec - The Use Of Weight Loss Herbs
Nothing has garnered more attention in today's world than the success or failures of weight loss pro - A Simple Acid Relux Cure
Many people today are afflicted with heartburn. If they eat food that is too spicy, they get heartbu - Five Effective Household Back Pain Treatments
Back pain treatment comes in lots of forms, from exercise to pain mediction. Standard and most wides - Herbal Remedies - Can They Cure What Ails You?
You've probably heard about herbal remedies before and how they can treat a variety of health proble - Natural Relief for Tinnitus - What are your Choices
Natural Relief For Tinnitus - Alternative Options Did you know that there are an estimated 50 t - Birthing Around the World
Since ancestral times, different cultures showed off different customs and beliefs around the miracl